Pickering Laboratories Guaranteed Chemistry

Quality Guaranteed Pickering Laboratories HPLC post-column instruments and solutions products catalog for environmental, pharmaceutical and biochemical laboratories.
     
 

 

 

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Part of the complete integrated system of instruments, chemicals, columns, methods and support from Pickering Laboratories.

The Pinnacle PCX Delta Series is an optimized HPLC Post-column derivatization system for analysis of Amino Acids, Carbamates, Mycotoxins, Antibiotics and many other applications. This completely new instrument is the culmination of Pickering Laboratories’ 25 years of experience in Post-Column analysis product manufacture.  Each component is specifically designed to optimize the sensitivity and selectivity of post column analysis. 

Only Pickering Laboratories offers the complete package of chemicals, columns, methods and post-column systems. Because each part of the method is designed to work together, Pickering Laboratories can offer the extraordinary promise that the analysis is guaranteed to work for the intended application.

The Pinnacle PCX is an optimized HPLC Post-column derivatization system for analysis of Amino Acids, Carbamates, Mycotoxins, Antibiotics and many other applications.

The Pinnacle PCX reflects the ease of use, reliability and ruggedness you have come to expect from Pickering Laboratories.

System design advancements result in optimized analysis:

 The electronic syringe pump provides true pulse-free flow for superior sensitivity and
    consistency. The pump cylinder and head is made from a single piece of inert
    ceramic for durability and non-reactivity.

  Electronic valves eliminate troublesome check valves and allow automated
    pump flushing.

  The quick-change reactor cartridge makes application switching easy and
    replacements quick and inexpensive.

  The Column oven utilizes circulating air for consistency of heating and quick cooling.

  Inert flow path extends system life and reduces maintenance.

  The PCX Control software allows for precise control of the reagent delivery
    and conservation.

  Column oven temperature gradient programming improves separation and run times.
    Pinnacle PCX is the only Post-column system with this feature.

  Works with any HPLC system.

FEATURE HIGHLIGHT

The Pinnacle PCX has a column oven capable of Programmable Temperature gradients. This feature is useful in Amino Acid Analysis by enabling additional flexibility when optimizing methods. Using the temperature gradient program allows for improved separation, shortened analysis time and fine-tuning the method for specific compound detection.

The Chromatogram in figure 1 demonstrates some of the clear advantages of the temperature gradient program. Compared to the standard method without the temperature gradient the total run time is 25% shorter. Additionally, separation is improved.

With the temperature gradient program you are able to focus on different areas of the chromatogram for your specific compound of interest.

 

Figure 1. High-efficiency Lithium for Physiological samples using temperature gradient

 

1. Phosphoserine

2. Taurine

3. Phosphoethanolamine

4. Urea

5. Aspartic acid

6. Hydroxyproline

7. Threonine

8. Serine

9. Aspargine

10. Glutamic acid

11. Glutamine

12. Sarcosine

13. a-Aminoadipic acid

14. Proline

15. Glycine

16. Alanine

17. Citrulline

18. α-Amino-n-butyric acid

19. Valine

20. Cystine

21. Methionine

22. Allo-isoleucine

23. Cystathionine

24. Isoleucine

25. Leucine

26. Tyrosine

27. Phenylalanine

28. β-Alanine

29. β-Amino-i –butyric acid

30. Homocystine

31. γ-Aminobutyric acid

32. Tryptophan

33. Ethanolamine

34. Hydroxylysines

35. Ammonia

36. Creatinine

37. Ornithine

38. Lysine

39. Histidine

40. 3-Methylhistidine

41. 1-Methylhistidine

42. Anserine

43. Carnosine

44. Homocarnosine

45. Arginie

 

PINNACLE PCX SPECIFICATIONS

PINNACLE PCX SPECIFICATIONS

Dimensions: 21.25” H x 10.5” W x
  18.25” D

• Weight: 60 lbs – Duplex

• Electrical: 100-120V, 50/50 Hz, 1.7 A,
  200 W or 200-240 V, 50/60 Hz, 0.8 A,
  200 W

• Mains voltage ± 10% of nominal

• Installation (over voltage) category II,
  pollution degree 2

• Indoor use only

• Environmental: Altitude up to 6500 ft

• Ambient Temperature 2°- 40° C

• Relative humidity up to 80% at 31°C.

REAGENT PUMPS

• True pulse-free syringe pump

• Single piece ceramic barrel

• Completely inert flow path

• Maximum operating pressure 500 psi

• Programmable flow-rate

• Flow range: 50 µL to 1500 µL/minute

• Refill cycle of 60 seconds

• Automatic piston wash

• Automatic reagent flush cycle

• No check valves

CONTROL

• Computer controlled

• Windows PC with 98, 2000, NT, XP

• Serial RS232 connection or network

REACTOR

• Heated reactor for temperature from 5° C
  above ambient to 130° C

• Easy replacement coil cartridges

• Range of reactor dwell volumes;
  0.1 mL to 3mL

• Reaction coil withstands up to 42 bar
  (600 psi) inlet pressure at 130° C

• Thermal safety switch limits temperature
  to 150° C to prevent damage

• Fast response

SAFEGUARDS

• In-line check valve: Prevents reagent
  back flow into the column when
  HPLC pressure drops

• Replaceable filters prevent column
  and reagent fouling

• Post-column system over pressure:
  A pre-calibrated relief valve opens at
  35 bar (500 psi) to prevent rupture of the
  post-column reactor tubing in the event of
  down-stream blockage

• Back-pressure regulator: Applies 7 bar
  (100 psi) to the detector flow cell outlet
  (waste) to prevent detector noise and
   precipitation due to out-gassing or boiling

 

COLUMN HEATER AND REACTOR CONTROLLER

• Heater accepts up to 6 or 8 mm OD
  (0.25 or 0.31 inch) x 50-250 mm
  in length (column and guard)

• Programmable Temperature gradient

• Temperature holds within ± 0.4°C from
  the set point. Could be set with 1° C
  resolution from 5° C above ambient to
  75° C

• Easy column access

INSTRUMENT PACKAGE AND FLOW PATH

• Advanced fluidics valve
  management system

• Easy access to internal components

• Standard fittings

• Post-column pressure relief valves

• Side panels easily removed for service

• Integrated Reagent reservoir tray

• Corrosion proof pan and panels

DISPLAY

• Back lit LCD

• Real time temperature and
  pressure display

• System Status icons

• Simple system control interface

GAS PRESSURE MANIFOLD AND REGULATOR

• Panel mount manifold

• Regulator maintains 0.3 bar (3-5 psi) on
  reagent reservoirs with 3-5 bar
  (45-75 psi) source pressure

• Safety Pressure-relief valve opens at 1
  bar (14 psi)

• Manifold has two 1/4-28 fittings

• Gas lines with anti-syphon valves

PRESSURIZED REAGENT RESERVOIR

• One liter capacity (2 and 5 L reservoirs
   available)

• Maintained under inert gas pressure to
  inhibit oxidation of sensitive reagents

• Valve built into reservoir cap permits
  sparging during reagent preparation

• Reagent reservoirs fitted with 3.1 mm
  (1/8”) OD (oxygen-impermeable) SARAN
  tubing for oxygen-sensitive reagents

 

 PINNACLE PCX CATALOG INFORMATION

CATALOG NO.

APPLICATION

REAGENT PUMP

REACTOR VOLUME

VOLTAGE

1153-1011 1153-1012

Amino Acids (OPA detection), Aminoglycoside Antibiotics, Biogenic Amines, Polyamines, Paraquat/Diquat

Single

0.15 mL

120 V
240 V

1153-1021 1153-1022

Amino Acids (TRIONE® Ninhydrin detection), Ochratoxin A, Formaldehyde

Single

0.5 mL

120 V
240 V

1153-1031 1153-1032

Mycotoxins including Aflatoxins & Fumonisins

Single

1.4 mL

120 V
240 V

1153-1041 1153-1042

Cholesterol

Single

Knitted 2.8 mL

120 V
240 V

1153-1051 1153-1052

Carbamate Pesticides, Glyphosate Herbicide, Streptomycin, (OPA detection)

Dual

0.5 mL

120 V
240 V

1153-1091 1153-1092

Micro System for Carbamate Pesticides & Glyphosate Herbicide

Dual

0.1 mL

120 V
240 V

1153-1061 1153-1062

Paralytic Shellfish Toxins Oshima Method

Dual

2.0ml

120 V
240 V

1153-1071 1153-1072

Trichothecene Mycotoxins

Dual

Knitted 1.2 & 1.6 mL

120 V
240 V

1153-1081 1153-1082

Polyether Antibiotics

Dual

1.4 mL

120 V
240 V

Note: Columns and chemicals sold separately

 

 

 

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