Chromatographic Grade™

For derivatization of primary amino groups

Naphthalene-2,3-dicarboxaldehyde reacts with primary amines in presence of a nucleophile (e.g., mercaptan) and forms highly fluorescent 1-Alkylbenz-2-thioalkyl[f]isoindole derivatives.

This reagent is especially effective for post-column or precolumn derivatization of proteins, peptides and other large amines since the derivative is stable and doesn’t internally quench.

Naphthalenedialdehyde can also be used as a reagent for chemiluminescence analysis.