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Thiofluor™ 2-(Dimethylamino)ethanethiol HCl

Overview

img-genericThiofluor™ 2-(Dimethylamino)ethanethiol HCl 

N,N-Dimethyl-2-Mercaptoethylamine Hydrochloride – Chromatographic Grade™ For Automated Post-Column Derivatization of Primary Amines

Primary amines form highly fluorescent adducts when reacted with o-Phthalaldehyde (OPA) and a mercaptan under basic conditions.

The products of this reaction, 1-alkyl-2-thioalkyl-subsitituted isoindoles, exhibit optimal excitation at 330 nm and maximal emission at 465 nm.

Pickering’s Thiofluor™ 2-(Dimethylamino)ethanethiol HCl, a solid, nearly odorless nucleophile, is a superior substitute for 2-Mercaptoethanol in the preparation of OPA reagents. It forms a more stable reagent and a longer-lasting fluorophore with OPA than does 2-Mercaptoethanol, yet it has the same fluorescence properties.

Unlike the volatile 2-Mercaptoethanol, Thiofluor™ will not migrate through the gas manifold and regulator of the OPA reagent pressurization system.

Two grams of Thiofluor™ 2-(Dimethylamino)ethanethiol HCl is equivalent to 1 mL of 2-Mercaptoethanol.


 
   

 

Pricing & Ordering

 

Pricing & Ordering

THIOFLUOR™ CATALOG INFORMATIONLogin for Prices

Catalog #

Description

Quantity

3700-2000

Thiofluor™, 10 g

each (10 g/bottle)


 
 

 

 
 
 

 

 

 

 

Retention Times
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Open for Business: COVID-19 Update

As of right now, Pickering Laboratories, Inc. will remain open during the “Shelter in Place” order for Santa Clara County so as to provide other essential businesses with the support and supplies necessary to operate, including hospitals and clinical laboratories.

Our inventory levels and response times are currently normal. Responsiveness is subject to change and orders may need to be prioritized accordingly to supply essential businesses.

Thank you for your patience and for your business as we all work together through this difficult time. Please contact us with any questions you may have.

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Phone: 650-694-6700