Fluorescamine – High-Purity Derivatization Reagent for Sensitive Post-Column Analysis

Fluorescamine is a widely used derivatization reagent that reacts rapidly with primary amino groups to form highly fluorescent derivatives. It has been extensively utilized for post-column analysis of a broad range of analytes, including amino acids, peptides, proteins, and other amino-containing compounds such as cephalosporin antibiotics.

This reagent is particularly valuable for high-sensitivity analysis of large molecules such as proteins and peptides. The fluorescent derivatives formed do not undergo self-quenching, preserving the intensity of the fluorescent signal. This property enables reliable trace-level analysis of hormones and pharmaceuticals in blood and other biological matrices, as well as use in purity confirmation assays.

In post-column trace analysis, reagent quality is critical to minimizing background signal and preventing analytical interferences. Pickering Laboratories specializes in high-purity derivatization reagents and is proud to announce the addition of highly purified crystalline fluorescamine to our product catalog.