Category Archives: maintenance

Replacing the Over-pressure Relief Valve Cartridge

Cleaning and Reassembly of the Over-pressure Relief Valve

  1. Remove the tubing connections to the Mixing Manifold. Use a 3/32” hex driver to remove the 2 screws holding the Mixing Manifold to the chassis. Use a 3/8” wrench to remove the end cap and discard the old Over-pressure Relief Valve Cartridge. Ultrasonicate the Mixing Manifold for at least 30 minutes. Rinse well with DI water.
  2. Connect the outlet of your HPLC pump to the Mixing Manifold inlet and pump 100% water at 0.5mL/min to verify the Mixing Manifold is not clogged. If the Mixing Manifold is still clogged after cleaning in an ultrasonicating bath, replace the Mixing Manifold Assembly (PN 1452-0040).
  3. Turn off the HPLC flow and make sure there is no pressure on the Mixing Manifold. Insert the new OPRV cartridge, green side down, and screw on the end cap to 20”lbs of torque. To approximate this level of torque, first finger tighten, then tighten an additional 1/8-1/4 turn with a 3/8” wrench.
  4. To verify the opening pressure of the Over-pressure Relief Valve, plug the two side inlets of the Mixing Manifold and turn on the HPLC pump to 0.5mL/min. Allow the pressure to slowly rise. The Over-pressure Relief Valve should open around 485psi. If the opening pressure is too low, tighten an additional 1/8 of a turn with a 3/8” wrench.

David Mazawa
Technical Support Chemist
Pickering Laboratories, Inc.
1280 Space Park Way
Mountain View, CA 94043 USA
Phone: (650)694-6700 ext. 710
Fax: (650)968-0749


Pinnacle Preventative Maintenance

Keep your Pinnacle in good condition and minimize downtime by performing annual maintenance. Performing Preventative Maintenance on your Pinnacle PCX is easy to accomplish with the Kits and Instruction we provide. Refer to the Maintenance Section of the Pinnacle Manual for details on performing the maintenance. Contact Pickering Laboratories Technical Support with any questions. 800-654-3330, 650-694-6700, or email
Below you can find a general maintenance schedule. Your maintenance schedule will depend on usage. If you use the Pinnacle PCX 24×7, you may want to perform the Preventative Maintenance more often.

Maintenance Schedule

Routine Maintenance

         Check for leaks every day
         Replace Flush and Piston Wash reservoirs every week
         Record operating pressures in a daily log book

Preventative Maintenance

         Replace Valve and Pump Seals every 12 months
         Replace the 10um Reagent Frits every 3 months
         Change the tubing every 24 months

Part Numbers

1000-1003               Kit, PM Service, Pinnacle Single Pump (Pump seals, Valve seals, and replacement filter)
1000-1004               Kit, PM Service, Pinnacle Dual Pump (Pump seals, Valve seals, and replacement filter)
1100-0500               Tubing Kit, Pinnacle Dual Pump
1100-0501               Tubing Kit, Pinnacle Single Pump
1452-0122               Pump Seal Kit, Pinnacle
1452-0200               Valve Seal Tool, Pinnacle (Tool only)
1452-0201               Valve Seals kit, Pinnacle (Seals only)
1452-0202               Valve Maintenance Kit, Pinnacle (seals and tool)
3102-9040               Replacement Reagent 10um Filter
1452-0200               Valve Seal Tool

Parts Lookup

Please try our Parts Lookup on our website if you ever need to find a part number. The Parts Lookup is located on our website. Start at
Select Parts Lookup under the Service & Support menu
Or, you can also find the Parts Lookup under the Products menu.
Select the Parts Lookup from the Replacement Components menu on the left side of the page.
Next, choose which instrument you are using.
Once you are in the Parts Lookup, simply click on a part or drag you mouse over the part of interest to see the part numbers.

David Mazawa
Technical Support Chemist
Pickering Laboratories, Inc.
1280 Space Park Way
Mountain View, California 94043 USA
Phone: 650-694-6700, ext. 710
Fax: 650-968-0749